The influenza virus can trigger a powerful immune response in the body, which leads to characteristic flu symptoms such as muscle and joint aches. When the virus enters the body, it triggers an inflammatory response that causes blood vessels to become leaky. This allows immune cells to travel to the site of infection and attack the virus.

The inflammation caused by the flu also affects nerves in the body, making them more sensitive to pain. This increased sensitivity can intensify and prolong the feeling of muscle and joint aches, making them feel even more uncomfortable for those who are suffering from flu.

Understanding how inflammation plays a role in flu symptoms can be helpful in developing new treatments for the illness. Over-the-counter pain relievers that reduce inflammation may help alleviate some of the discomfort associated with flu symptoms. By targeting this specific aspect of the immune response, researchers may be able to develop even more effective treatments for future outbreaks of influenza.